Metabolic Constituents of Urinary Stone Composition in Sudanese Children

Author

By Ghada A. Elfadil, Muntasir E. Ibrahim, Salah AM. Ahmed.

Abstracts

Objectives: The aim of this study was to show the biological characteristics of pediatric urolithiasis in Sudanese patientís population and evaluation of some metabolic risk factors. Materials and Methods: We analyzed prospectively urinary stones from 175 consecutive children (129 males, 46 females), aged 3 months to 16 years. Patients were reviewed in Soba Teaching Hospital, Khartoum state Sudan, during the period October 2005-May 2009. The chemical analysis of stones was carried out by Urinary Calculi Analysis Kit, manufacturer DiaSys Diagnostic system GmbH. One hundred and thirty blood samples (80 patients, 50 controls) were collected from patients with renal stone to screen some metabolic risk factors, serum calcium, serum phosphate, serum uric acid, and serum creatinine. Fifty samples, of 24 hours urine collection (30 patients, 20 controls) were collected to determine the excretion of urine calcium, phosphate and uric acid. It was analyzed by auto analyzer Cobas Integra 400 Plus. Statistical Analysis: Statistical analysis of data was carried out using software SPSS 11.0 for Windows. Statistical significance was determined using chi-square test & Fisher exact test.

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